Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | RXRB | P28702 | 4/20 | 0.35 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | IL6 | P05231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211015 | 0.82 | TNF (0.51) | TNFIL6MEN1KMT2AHPGD | |
| SCHEMBL3855365 | 0.72 | CYP26A1 (0.37) | GAAPARP10PARP11ACHE | |
| SCHEMBL8911116 | 0.70 | PLAU (0.37) | KDM4EMEN1NPC1MAPTKMT2A | |
| SCHEMBL29004545 | 0.70 | KIF11 (0.44) | RXRARXRBRXRGDGAT1KCNH2 | |
| SCHEMBL16399474 | 0.70 | KIF11 (0.47) | RXRARXRBRXRGKDM4EMEN1 | |
| SCHEMBL2261719 | 0.67 | CYP1A2 (0.41) | MEN1NPC1MAPTKMT2AGAA | |
| SCHEMBL2258288 | 0.67 | CYP1A2 (0.41) | MEN1NPC1MAPTKMT2AGAA | |
| SCHEMBL8910275 | 0.67 | TAAR1 (0.43) | PARP10PARP11NOTUM | |
| SCHEMBL11480321 | 0.66 | CYP1A2 (0.40) | MEN1NPC1MAPTKMT2AGAA | |
| SCHEMBL11480324 | 0.66 | CYP1A2 (0.40) | MEN1NPC1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |