Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Bromo Acetate SCHEMBL30028633 | 0.93 | ALDH1A1 (0.44) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL30028689 | 0.86 | MEN1 (0.43) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL5114769 | 0.85 | MEN1 (0.40) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL8912197 | 0.84 | KMT2A (0.45) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL5121809 | 0.81 | GSK3A (0.40) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| Ethyl Bromo Acetate SCHEMBL30029142 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| Ethyl Bromo Acetate SCHEMBL30029347 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL14014876 | 0.77 | MEN1 (0.33) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL5653075 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2APOLBLMNAALDH1A1 | |
| SCHEMBL8914329 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2APOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175402-A1 | QUINUCLIDINE-3-ONE DERIVATIVES | APREA THERAPEUTICS AB (SE) | 2022-08-25 | — | — | WO | disclosed |
| US-5641786-A | Quinuclidine derivatives | LOWE III JOHN ADAMS (US) | 1997-06-24 | — | — | US | disclosed |
| US-5422354-A | Quinuclidine derivatives | PFIZER INC (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0540526-B1 | QUINUCLIDINE DERIVATIVES | PFIZER (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0540526-A1 | QUINUCLIDINE DERIVATIVES. | PFIZER (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001688-A1 | QUINUCLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-02-06 | — | — | WO | disclosed |