Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028689 | 0.94 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| Ethyl Bromo Acetate SCHEMBL30029347 | 0.93 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9698278 | 0.88 | ENPP2 (0.38) | KMT2AALDH1A1KDM4ESMN1; SMN2POLB | |
| Ethyl Bromo Acetate SCHEMBL30029142 | 0.87 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5114769 | 0.86 | MEN1 (0.40) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL1268069 | 0.84 | ALDH1A1 (0.42) | KMT2AALDH1A1KDM4EPOLBCYP2D6 | |
| SCHEMBL8912207 | 0.84 | MEN1 (0.38) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL5121809 | 0.82 | GSK3A (0.40) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8912481 | 0.78 | KMT2A (0.40) | KMT2AALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL14446813 | 0.78 | TP53 (0.39) | ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175402-A1 | QUINUCLIDINE-3-ONE DERIVATIVES | APREA THERAPEUTICS AB (SE) | 2022-08-25 | — | — | WO | disclosed |
| US-5641786-A | Quinuclidine derivatives | LOWE III JOHN ADAMS (US) | 1997-06-24 | — | — | US | disclosed |
| US-5422354-A | Quinuclidine derivatives | PFIZER INC (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0540526-B1 | QUINUCLIDINE DERIVATIVES | PFIZER (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0540526-A1 | QUINUCLIDINE DERIVATIVES. | PFIZER (US) | 1993-05-12 | — | — | EP | disclosed |