SCHEMBL891224

SCHEMBL891224

Cc1cc(CN=C=O)c(CN=C=O)c(C)c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21569372 0.79 PGK1 (0.33)
SCHEMBL21623883 0.79 TRPA1 (0.33)
SCHEMBL459569 0.79 NPSR1 (0.37)
SCHEMBL8763309 0.77 CYP3A4 (0.32)
SCHEMBL460694 0.76 CYP3A4 (0.32)
SCHEMBL427584 0.75 PGK1 (0.42)
SCHEMBL29387247 0.74
SCHEMBL11043279 0.74 GABRA1 (0.34)
SCHEMBL434565 0.74
SCHEMBL20144 0.74 CYP3A4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3491179-B1 SILICONE OIL ELIMINATION FROM SPANDEX POLYMER SPINNING SOLUTIONS THE LYCRA COMPANY UK LTD (GB) 2020-12-02 EP claimed
US-20190301056-A1 SILICONE OIL ELIMINATION FROM SPANDEX POLYMER SPINNING SOLUTIONS A&AT LLC (US) 2019-10-03 US claimed
EP-3491179-A1 SILICONE OIL ELIMINATION FROM SPANDEX POLYMER SPINNING SOLUTIONS A&AT UK Limited (GB) 2019-06-05 EP claimed
EP-2002850-B1 Adhesive formulations COVIDIEN LP (US) 2017-04-05 EP claimed
EP-2570441-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2015-04-01 EP claimed
EP-2144576-B1 BIODEGRADABLE MACROMERS COVIDIEN LP (US) 2014-06-18 EP claimed
US-8748558-B2 Biodegradable macromers COVIDIEN LP (US) 2014-06-10 US claimed
EP-2111877-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2013-09-18 EP claimed
EP-2009037-B1 Foam control for synthetic adhesive/sealant COVIDIEN LP (US) 2013-08-14 EP claimed
EP-2177552-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2013-03-27 EP claimed
WO-2008134276-A1 BIODEGRADABLE MACROMERS TYCO HEALTHCARE GROUP LP (US) 2008-11-06 WO claimed
EP-1968617-A2 BIOCOMPATIBLE TISSUE SEALANTS AND ADHESIVES Tyco Healthcare Group LP (US) 2008-09-17 EP claimed
EP-1960469-A2 BIOABSORBABLE COMPOUNDS AND COMPOSITIONS CONTAINING THEM Tyco Healthcare Group, LP (US) 2008-08-27 EP claimed
WO-2007067623-A2 BIOCOMPATIBLE TISSUE SEALANTS AND ADHESIVES TYCO HEALTHCARE GROUP LP (US) 2007-06-14 WO claimed
WO-2007067624-A2 BIOABSORBABLE COMPOUNDS AND COMPOSITIONS CONTAINING THEM TYCO HEALTHCARE GROUP LP (US) 2007-06-14 WO claimed
US-20070128152-A1 Biocompatible tissue sealants and adhesives TYCO HEALTHCARE GROUP LP 2007-06-07 US claimed
US-20070129505-A1 Bioabsorbable compounds and compositions containing them TYCO HEALTHCARE GROUP LP 2007-06-07 US claimed
US-5231159-A HIGH TEMPERATURE RESISTANT MOLDED ELASTOMER THE GATES RUBBER COMPANY (US) 1993-07-27 US claimed
EP-0517908-A1 HIGH TEMPERATURE RESISTANT MOLDED ELASTOMER THE GATES RUBBER COMPANY (US) 1992-12-16 EP claimed
WO-1992012191-A1 HIGH TEMPERATURE RESISTANT MOLDED ELASTOMER THE GATES RUBBER COMPANY (US) 1992-07-23 WO claimed