SCHEMBL891246

SCHEMBL891246

CC(C)=CCCC(C)=CC(O)C=O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 3/20 0.47
ATM Q13315 1/20 0.47
ALOX15 P16050 3/20 0.47
MEN1 O00255 2/20 0.47
CYP3A4 P08684 2/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 2/20 0.45
UGT1A1 P22309 1/20 0.45
SQLE Q14534 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891162 1.00 ALDH1A1 (0.53) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL4585540 0.80 KMT2A (0.61) ALDH1A1KMT2AKDM4EALOX15MEN1
SCHEMBL2322202 0.80 FNTA (0.59) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL11584608 0.79 KMT2A (0.58) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL11586065 0.79 KMT2A (0.58) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL356392 0.79 KMT2A (0.58) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL11448116 0.78 KMT2A (0.48) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL11448115 0.78 KMT2A (0.48) ALDH1A1KMT2AKDM4EATMALOX15
SCHEMBL127329 0.78 KMT2A (0.58) ALDH1A1KMT2AKDM4EALOX15MEN1
SCHEMBL30990927 0.78 KMT2A (0.58) ALDH1A1KMT2AKDM4EALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621462-B1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR PROCTER & GAMBLE (US) 2020-02-12 EP claimed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP claimed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO claimed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US claimed
EP-3383502-B1 ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF COLGATE PALMOLIVE CO (US) 2025-03-05 EP disclosed
EP-3355849-B1 ORAL CARE COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS COLGATE PALMOLIVE CO (US) 2021-03-10 EP disclosed
EP-2621462-B1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR PROCTER & GAMBLE (US) 2020-02-12 EP disclosed
US-20180280263-A1 Oral Care Compositions and Methods of Using the Compositions COLGATE-PALMOLIVE COMPANY (US) 2018-10-04 US disclosed
US-9937115-B2 Oral care compositions with improved flavor THE PROCTER & GAMBLE COMPANY (US) 2018-04-10 US disclosed
US-9937115-B2 Oral care compositions with improved flavor THE PROCTER & GAMBLE COMPANY (US) 2018-04-10 US disclosed
US-9937115-B2 Oral care compositions with improved flavor THE PROCTER & GAMBLE COMPANY (US) 2018-04-10 US disclosed
US-9937115-B2 Oral care compositions with improved flavor THE PROCTER & GAMBLE COMPANY (US) 2018-04-10 US disclosed
EP-2621462-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR The Procter and Gamble Company (US) 2013-08-07 EP disclosed
CN-103140209-A Oral care compositions with improved flavor PROCTER & GAMBLE 2013-06-05 CN disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed
WO-2012044728-A1 ORAL CARE COMPOSITIONS WITH IMPROVED FLAVOR THE PROCTER & GAMBLE COMPANY (US) 2012-04-05 WO disclosed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US disclosed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US disclosed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US disclosed
US-20120082628-A1 Oral Care Compositions With Improved Flavor THE PROCTER & GAMBLE COMPANY 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120082628-A1 Oral Care Compositions With Improved Flavor TRPA1, TAS2R40, TAS2R30 ALDH1A1 1558/4885KMT2A 1953/4885KDM4E 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.