Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268069 | 0.83 | ALDH1A1 (0.42) | KMT2ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8912197 | 0.78 | KMT2A (0.45) | KMT2AALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL30028689 | 0.75 | MEN1 (0.43) | KMT2AALDH1A1KDM4EPOLBABL1 | |
| Ethyl Bromo Acetate SCHEMBL30029347 | 0.73 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL9698278 | 0.72 | ENPP2 (0.38) | KMT2ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5849383 | 0.72 | CHRM1 (0.42) | KMT2ACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6741911 | 0.71 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL13015335 | 0.71 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL6743581 | 0.71 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL4085410 | 0.71 | ALDH1A1 (0.43) | KMT2ACHRM1ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641786-A | Quinuclidine derivatives | LOWE III JOHN ADAMS (US) | 1997-06-24 | — | — | US | disclosed |
| US-5422354-A | Quinuclidine derivatives | PFIZER INC (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0540526-B1 | QUINUCLIDINE DERIVATIVES | PFIZER (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0540526-A1 | QUINUCLIDINE DERIVATIVES. | PFIZER (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001688-A1 | QUINUCLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-02-06 | — | — | WO | disclosed |