Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303224 | 1.00 | MAPT (0.50) | MAPTSMN1; SMN2THRBTHRANPC1 | |
| SCHEMBL8913312 | 0.99 | MAPT (0.51) | MAPTSMN1; SMN2THRBTHRANPC1 | |
| SCHEMBL8912855 | 0.93 | LMNA (0.56) | MAPTSMN1; SMN2THRBNPC1LMNA | |
| SCHEMBL8915996 | 0.92 | LMNA (0.58) | MAPTSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL8913741 | 0.90 | MAPT (0.49) | MAPTSMN1; SMN2THRBTHRANPC1 | |
| SCHEMBL9304067 | 0.89 | LMNA (0.54) | MAPTSMN1; SMN2THRBNPC1LMNA | |
| SCHEMBL8913572 | 0.88 | MAPT (0.54) | MAPTSMN1; SMN2THRBTHRANPC1 | |
| SCHEMBL8912149 | 0.86 | F2 (0.44) | MAPTSMN1; SMN2THRBTHRANPC1 | |
| SCHEMBL8913492 | 0.86 | MAPT (0.55) | MAPTSMN1; SMN2THRBTHRANPC1 | |
| SCHEMBL9305454 | 0.85 | LMNA (0.63) | MAPTSMN1; SMN2NPC1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5277838-A | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |