SCHEMBL9304067

SCHEMBL9304067

CCCCOc1ccc(OC(=O)c2ccc(CCC[Si](C)(C)O[Si](C)(C)C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.54
NPC1 O15118 4/20 0.54
CYP1A2 P05177 3/20 0.54
CYP2C19 P33261 3/20 0.54
CYP2C9 P11712 2/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPT P10636 5/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
KMT2A Q03164 4/20 0.53
NFKB1 P19838 3/20 0.53
NFKB2 Q00653 3/20 0.53
RELA Q04206 3/20 0.53
PRSS1 P07477 1/20 0.51
ACR P10323 1/20 0.51
TSHR P16473 1/20 0.49
THRB P10828 1/20 0.47
POLB P06746 1/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8912855 0.94 LMNA (0.56) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL8915996 0.93 LMNA (0.58) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL8921077 0.93 MAPT (0.56) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL8913741 0.92 MAPT (0.49) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL8913312 0.91 MAPT (0.51) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL9303224 0.89 MAPT (0.50) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL8913267 0.89 MAPT (0.50) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL9305454 0.89 LMNA (0.63) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL9685119 0.89 LMNA (0.63) LMNANPC1CYP1A2CYP2C19CYP2C9
SCHEMBL9686645 0.88 LMNA (0.65) LMNANPC1CYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5277838-A Silylated benzoic acid derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-01-11 US disclosed
US-5106530-A Liquid crystals Consortium Fur Elektrochemische Ind. (DE) 1992-04-21 US disclosed