Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16577075 | 0.86 | MEN1 (0.62) | ALDH1A1LMNAMAPTCHRM2CHRM4 | |
| SCHEMBL5311175 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNATSHRMAPTKDM4E | |
| SCHEMBL211276 | 0.82 | KCNT1 (0.56) | ALDH1A1LMNATSHRMAPTCHRM2 | |
| SCHEMBL22315264 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRMAPTKDM4E | |
| SCHEMBL5312343 | 0.81 | ALDH1A1 (0.70) | ALDH1A1LMNATSHRMAPTKDM4E | |
| SCHEMBL31254120 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRMAPTCETP | |
| SCHEMBL31254088 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRMAPTCETP | |
| SCHEMBL29200534 | 0.80 | PTPN2 (0.70) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL8890641 | 0.79 | ABCB1 (0.50) | ALDH1A1LMNAMAPTCHRM2CHRM4 | |
| SCHEMBL31254104 | 0.79 | ALDH1A1 (0.49) | ALDH1A1LMNATSHRCETPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |