Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913316 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTACKR3CHRM2 | |
| SCHEMBL7776183 | 0.79 | GPR119 (0.47) | ABCB1ALDH1A1MAPTHTTNPC1 | |
| SCHEMBL8893240 | 0.76 | RAD52 (0.46) | ALDH1A1MAPTMAPK1POLBLMNA | |
| SCHEMBL12408091 | 0.75 | ABCB1 (0.52) | ABCB1ALDH1A1MAPTHTTNPC1 | |
| SCHEMBL17276352 | 0.74 | FAAH (0.58) | NPC1 | |
| SCHEMBL16855862 | 0.74 | FAAH (0.58) | NPC1 | |
| SCHEMBL17861488 | 0.74 | ABCB1 (0.55) | ABCB1ALDH1A1MAPK1CHRM2CHRM4 | |
| SCHEMBL16469287 | 0.73 | BACE1 (0.53) | ABCB1MAPTL3MBTL1POLB | |
| SCHEMBL10319468 | 0.73 | BACE1 (0.53) | ABCB1MAPTL3MBTL1POLB | |
| SCHEMBL10319466 | 0.73 | BACE1 (0.53) | ABCB1MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |