Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.52 |
| ▸ | PNP | P00491 | 3/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517600 | 1.00 | ADORA3 (0.56) | ADORA3STING1PNPHPRT1POLB | |
| SCHEMBL9386094 | 1.00 | ADORA3 (0.56) | ADORA3STING1PNPHPRT1POLB | |
| SCHEMBL12642438 | 1.00 | ADORA3 (0.56) | ADORA3STING1PNPHPRT1POLB | |
| SCHEMBL9386090 | 1.00 | ADORA3 (0.56) | ADORA3STING1PNPHPRT1POLB | |
| SCHEMBL8913491 | 1.00 | ADORA3 (0.56) | ADORA3STING1PNPHPRT1POLB | |
| SCHEMBL21942766 | 0.89 | ADORA3 (0.52) | ADORA3STING1PNPHPRT1TK1 | |
| SCHEMBL22381969 | 0.89 | ADORA3 (0.52) | ADORA3STING1PNPHPRT1TK1 | |
| SCHEMBL20324662 | 0.85 | POLB (0.56) | ADORA3PNPHPRT1POLB | |
| SCHEMBL8912238 | 0.83 | ALDH1A1 (0.54) | ADORA3STING1HPRT1 | |
| SCHEMBL8913594 | 0.83 | ALDH1A1 (0.54) | ADORA3STING1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | claimed |
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | disclosed |