Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | TYMP | P19971 | 2/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445335 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8913594 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL9386090 | 0.83 | ADORA3 (0.56) | ADORA3STING1HPRT1 | |
| SCHEMBL8913491 | 0.83 | ADORA3 (0.56) | ADORA3STING1HPRT1 | |
| SCHEMBL6517600 | 0.83 | ADORA3 (0.56) | ADORA3STING1HPRT1 | |
| SCHEMBL9386094 | 0.83 | ADORA3 (0.56) | ADORA3STING1HPRT1 | |
| SCHEMBL12642438 | 0.83 | ADORA3 (0.56) | ADORA3STING1HPRT1 | |
| SCHEMBL8913486 | 0.83 | ADORA3 (0.56) | ADORA3STING1HPRT1 | |
| SCHEMBL2914087 | 0.82 | PAX8 (0.57) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL8709565 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAALBMAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | claimed |
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | disclosed |