Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | MYOF | Q9NZM1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447285 | 0.89 | RAB9A (0.42) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7449927 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL8804534 | 0.82 | KDM4E (0.41) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL8805992 | 0.82 | RAB9A (0.45) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7442181 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7441237 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7493819 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7442622 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7436869 | 0.78 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD | |
| SCHEMBL7444167 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4ENPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703071-A | Tropolone derivatives and pharmaceutical composition thereof for preventing and treating ischemic diseases | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |