Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911749 | 0.89 | ALDH1A1 (0.41) | ALDH1A1ELANESMN1; SMN2SLC15A1TSHR | |
| SCHEMBL8911940 | 0.88 | ALDH1A1 (0.41) | ALDH1A1ELANESMN1; SMN2SLC15A1TSHR | |
| SCHEMBL8912143 | 0.85 | ALDH1A1 (0.38) | ALDH1A1ELANESMN1; SMN2SLC15A1TSHR | |
| SCHEMBL8912045 | 0.85 | ALDH1A1 (0.43) | ALDH1A1ELANESMN1; SMN2TSHR | |
| SCHEMBL8911361 | 0.84 | NPSR1 (0.39) | ALDH1A1ELANESMN1; SMN2SLC15A1TSHR | |
| SCHEMBL8912018 | 0.84 | ALDH1A1 (0.39) | ALDH1A1ELANESMN1; SMN2RAB9A | |
| SCHEMBL8913640 | 0.83 | ATM (0.56) | ATM | |
| SCHEMBL8913772 | 0.83 | ITGB3 (0.39) | ALDH1A1RAB9A | |
| SCHEMBL8911896 | 0.83 | ATM (0.38) | ALDH1A1ELANESMN1; SMN2SLC15A1ATM | |
| SCHEMBL8911768 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |