SCHEMBL891381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2895076	0.83	PARP1 (0.41)	LMNATSHRALDH1A1NPC1KMT2A
	SCHEMBL6883224	0.81	HTT (0.46)	LMNACYP1A2TSHRCYP2C19ADORA3
	SCHEMBL891352	0.78	TRPM8 (0.40)	TSHRALDH1A1KMT2A
	SCHEMBL891260	0.77	AAK1 (0.40)	ALDH1A1KMT2A
	SCHEMBL891356	0.77	TAS1R3 (0.40)	ALDH1A1NPC1KMT2ARAB9A
	SCHEMBL17923426	0.74	AAK1 (0.41)	TSHRALDH1A1NPC1KMT2ARAB9A
	SCHEMBL4838147	0.71	CA1 (0.35)	CYP1A2TSHRALDH1A1NPC1KMT2A
	SCHEMBL15145872	0.71	ALDH1A1 (0.56)	TSHRALDH1A1NPC1HPGDKMT2A
	SCHEMBL17662314	0.71	KMT2A (0.73)	LMNACYP1A2TSHRCYP2C19ALDH1A1
	SCHEMBL4693865	0.71	SMN1; SMN2 (0.50)	LMNATSHRALDH1A1NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.