Biphenyl

Biphenyl

SCHEMBL8913858

C[SiH](C)c1ccc(C(=O)O)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.53
TSHR P16473 2/20 0.52
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
MAPT P10636 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
SRD5A2 P31213 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
TP53 P04637 1/20 0.50
KMO O15229 1/20 0.48
RXRA P19793 3/20 0.47
RXRB P28702 3/20 0.47
RXRG P48443 1/20 0.47
BCL2 P10415 1/20 0.47
MKNK1 Q9BUB5 1/20 0.47
MKNK2 Q9HBH9 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27893882 0.91 BCL2L1 (0.56) EGFRTSHRSMN1; SMN2SRD5A2TP53
SCHEMBL8914727 0.89 TSHR (0.63) TSHRDAONAPRTSMN1; SMN2SRD5A2
SCHEMBL8912234 0.87 CA1 (0.62) MAPTSMN1; SMN2CES2CES1RXRA
SCHEMBL8912728 0.85 AR (0.48) EGFRTSHRMAPTSMN1; SMN2NPC1
Terephthalic Acid SCHEMBL340493 0.84 TSHR (0.72) EGFRTSHRDAONAPRTMAPT
Terephthalic Acid SCHEMBL251149 0.84 TSHR (0.72) EGFRTSHRDAONAPRTMAPT
Ethane SCHEMBL27330257 0.82 MAPT (0.67) EGFRTSHRDAONAPRTMAPT
Terephthalic Acid SCHEMBL10780545 0.82 EGFR (0.72) EGFRTSHRDAONAPRTMAPT
SCHEMBL7155730 0.82 EGFR (0.72) EGFRTSHRDAONAPRTMAPT
Biphenyl SCHEMBL5186249 0.82 EGFR (0.72) EGFRTSHRDAONAPRTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35462-E Silylated benzoic acid derivatives CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) 1997-02-25 US disclosed
US-5304667-A Cyclosiloxanes containing mesogenic side groups CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-04-19 US disclosed
US-5277838-A Silylated benzoic acid derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-01-11 US disclosed
US-5221759-A CYCLOSILOXANES CONTAINING MESOGENIC SIDE GROUPS CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1993-06-22 US disclosed
US-5106530-A Liquid crystals Consortium Fur Elektrochemische Ind. (DE) 1992-04-21 US disclosed