Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.66 |
| ▸ | PRKCG | P05129 | 3/20 | 0.66 |
| ▸ | PRKCB | P05771 | 3/20 | 0.66 |
| ▸ | PRKCA | P17252 | 3/20 | 0.66 |
| ▸ | PRKCH | P24723 | 3/20 | 0.66 |
| ▸ | PRKCI | P41743 | 3/20 | 0.66 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.66 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.66 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.66 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.66 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | PRKACA | P17612 | 2/20 | 0.66 |
| ▸ | PRKACG | P22612 | 2/20 | 0.66 |
| ▸ | PRKACB | P22694 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663930 | 0.90 | KMT2A (0.70) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5663391 | 0.86 | KMT2A (0.66) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL29162292 | 0.85 | NSD2 (0.61) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL9541290 | 0.84 | PRKCG (0.86) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL20026077 | 0.84 | NSD2 (0.70) | CYP3A4MAPK1NSD2NPY5R | |
| SCHEMBL29380289 | 0.83 | FLT3 (0.77) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL9544869 | 0.82 | LMNA (0.81) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL7433187 | 0.82 | PRKCA (0.60) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL9544846 | 0.82 | PRKACA (0.80) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL10983368 | 0.82 | PRKCG (0.73) | KMT2APRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663174-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF KINASES, ANTIARTHRITIC AGENTS | PHARNO-WEDROPHARM GMBH (DE) | 1997-09-02 | — | — | US | disclosed |
| WO-1993005014-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO-WEDROPHARM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |