Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | ACR | P10323 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912271 | 0.96 | NPC1 (0.60) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8914345 | 0.95 | MAPT (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8912760 | 0.92 | THRB (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1925571 | 0.90 | THRB (0.57) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20628415 | 0.89 | LMNA (0.60) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8913348 | 0.89 | THRB (0.61) | NPC1PRSS1ACRMAPTSMN1; SMN2 | |
| SCHEMBL8913503 | 0.89 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9878869 | 0.88 | MAPT (0.55) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9879247 | 0.88 | LMNA (0.63) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18540053 | 0.88 | THRB (0.49) | NPC1PRSS1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5277838-A | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |