Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914024 | 0.93 | L3MBTL1 (0.45) | GAAPSMD14L3MBTL1MAPTALDH1A1 | |
| SCHEMBL5109272 | 0.86 | CYP3A4 (0.52) | MAPTALDH1A1 | |
| SCHEMBL8916260 | 0.84 | MAPT (0.54) | GAAL3MBTL1TSHRMAPTALDH1A1 | |
| SCHEMBL8915650 | 0.84 | CYP3A4 (0.48) | GAAL3MBTL1POLBMAPTALDH1A1 | |
| SCHEMBL5120357 | 0.83 | PDE10A (0.42) | L3MBTL1MAPTALDH1A1KDM4EPDE10A | |
| SCHEMBL8914486 | 0.83 | KDM4E (0.49) | L3MBTL1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL5106665 | 0.83 | PDE10A (0.43) | L3MBTL1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL8914963 | 0.81 | L3MBTL1 (0.43) | GAAPSMD14L3MBTL1TSHRKMT2A | |
| SCHEMBL8915967 | 0.76 | ALDH1A1 (0.40) | GAAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8502779 | 0.75 | TSHR (0.60) | GAAPSMD14L3MBTL1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | claimed |
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |