SCHEMBL891427

SCHEMBL891427

O=C1c2ccccc2C(=O)N1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 2/20 0.50
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HTT P42858 1/20 0.43
POLB P06746 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
ALOX15 P16050 1/20 0.40
CASP3 P42574 1/20 0.40
CYP1A2 P05177 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
STAT6 P42226 1/20 0.39
HIF1A Q16665 1/20 0.39
PHLPP2 Q6ZVD8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15577172 0.81 ERCC1 (0.55) MEN1KMT2AALDH1A1POLBALOX15
SCHEMBL29025238 0.79 SCN2A (0.44) SCN2AMEN1KMT2AALDH1A1HTT
SCHEMBL27582192 0.77 CES1 (0.53) ALDH1A1HTTTP53BCHECES1
SCHEMBL13619924 0.76 POLB (0.42) SCN2AKMT2AALDH1A1HTTPOLB
SCHEMBL11665539 0.73 EHMT2 (0.45) SCN2AMEN1KMT2AALDH1A1POLB
SCHEMBL10620767 0.71 SCN2A (0.46) SCN2AMEN1KMT2ACTDSP1ALDH1A1
SCHEMBL10620771 0.71 SCN2A (0.46) SCN2AMEN1KMT2ACTDSP1ALDH1A1
Nitric Acid SCHEMBL11839157 0.71 CASP3 (0.61) SCN2AMEN1KMT2AALDH1A1HTT
SCHEMBL768174 0.71 CYP1A2 (0.48) SCN2AMEN1KMT2ACTDSP1ALDH1A1
SCHEMBL8115118 0.71 SCN2A (0.46) SCN2AMEN1KMT2ACTDSP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285608-A Preparation method of chiral 6-amino nicotine 恒信永基科技(深圳)有限公司 2025-01-10 CN claimed
CN-119076058-A Carbon intercalation iron phthalocyanine heterogeneous junction and preparation method and application thereof 南京大学 2024-12-06 CN claimed
EP-3397635-B1 METHODS FOR THE MANUFACTURE OF AN AROMATIC BISIMIDE AND A POLYETHERIMIDE SHPP GLOBAL TECH BV (NL) 2021-11-03 EP claimed
US-20210206747-A1 METHODS FOR THE MANUFACTURE OF AN AROMATIC BISIMIDE AND A POLYETHERIMIDE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-07-08 US claimed
CN-107903203-B Synthetic method of 3, 4-dinitrophthalimide 五邑大学 2020-06-19 CN claimed
EP-3397635-A1 METHODS FOR THE MANUFACTURE OF AN AROMATIC BISIMIDE AND A POLYETHERIMIDE SABIC Global Technologies B.V. (NL) 2018-11-07 EP claimed
CN-108587074-A High-melting-point electronic material 太仓双赢电子电气成套设备有限公司 2018-09-28 CN claimed
CN-107903203-A A kind of synthetic method of 3,4 pairs of nitrophthalimides 五邑大学 2018-04-13 CN claimed
WO-2017117449-A1 METHODS FOR THE MANUFACTURE OF AN AROMATIC BISIMIDE AND A POLYETHERIMIDE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-06 WO claimed
CN-106905914-A A kind of semi-intercrossing network polyimide resin composition and its membranaceous adhesive of preparation 成都正威新材料研发有限公司 2017-06-30 CN claimed
US-4933469-A Method for preparing oxybisphthalimides GENERAL ELECTRIC COMPANY (US) 1990-06-12 US claimed
US-4780544-A HEATING N-ORGANONITROPHTHALIMIDE IN PRESENCE OF APROTIC SOLVENT IN ALKALI METAL CARBOXYLATE GENERAL ELECTRIC COMPANY (US) 1988-10-25 US claimed
EP-0250981-A2 Method for making bisimides GENERAL ELECTRIC COMPANY (US) 1988-01-07 EP claimed
US-4455431-A Method for making bis-etherphthalimides GENERAL ELECTRIC COMPANY (US) 1984-06-19 US claimed
US-4054577-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1977-10-18 US claimed
US-4020069-A FROM BISPHENOL A AND A NITRO-PHTHALIMIDE, HYDROLYSIS GENERAL ELECTRIC COMPANY (US) 1977-04-26 US claimed
US-4017511-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1977-04-12 US claimed
US-3992406-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1976-11-16 US claimed
US-3957862-A FROM A NITRO-PHTHALIMIDE AND ALKALI DIPHENOXIDE GENERAL ELECTRIC COMPANY (US) 1976-05-18 US claimed
US-3933852-A Process for making N-methyl nitrophthalimides GENERAL ELECTRIC COMPANY (US) 1976-01-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210206747-A1 METHODS FOR THE MANUFACTURE OF AN AROMATIC BISIMIDE AND A POLYETHERIMIDE PAH, DDC, TNNI3K SCN2A 655/4885MEN1 1389/4885KMT2A 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.