SCHEMBL8914289

SCHEMBL8914289

Cc1cc(Cc2ccccc2O)c(O)c(Cc2c(C)c(Cc3cc(C)c(O)c(Cc4cc(C)cc(Cc5ccccc5O)c4O)c3C)cc(C)c2O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.51
HSPA5 P11021 2/20 0.46
IDH1 O75874 1/20 0.42
CYP2C9 P11712 3/20 0.40
CYP2C19 P33261 3/20 0.40
HIF1A Q16665 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 6/20 0.38
CNR2 P34972 1/20 0.38
HSD17B10 Q99714 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP1A2 P05177 1/20 0.36
KEAP1 Q14145 1/20 0.36
HPGD P15428 1/20 0.35
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278376 1.00 AMY1A (0.51) AMY1AHSPA5IDH1CYP2C9CYP2C19
SCHEMBL3642464 0.93 HSPA5 (0.53) AMY1AHSPA5IDH1HIF1ASMN1; SMN2
SCHEMBL1661235 0.87 AMY1A (0.71) AMY1AHSPA5CYP2C9CYP2C19HIF1A
SCHEMBL29199642 0.85 HSPA5 (0.55) AMY1AHSPA5IDH1HIF1ASMN1; SMN2
SCHEMBL7098334 0.85 AMY1A (0.47) AMY1AHSPA5CYP2C9CYP2C19HIF1A
SCHEMBL29290539 0.84 AMY1A (0.69) AMY1AHSPA5IDH1CYP2C9CYP2C19
SCHEMBL30375225 0.84 AMY1A (0.69) AMY1AHSPA5IDH1CYP2C9CYP2C19
SCHEMBL7758427 0.84 AMY1A (0.69) AMY1AHSPA5IDH1CYP2C9CYP2C19
SCHEMBL278748 0.84 AMY1A (0.46) AMY1AHSPA5CYP2C9CYP2C19HIF1A
SCHEMBL278377 0.84 AMY1A (0.46) AMY1AHSPA5CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9110758-A None JP disclosed
JP-H09110758-A HEXANUCLEAR NOVOLAC COMPOUND AND ITS PRODUCTION SUMITOMO CHEM CO LTD 1997-04-28 JP disclosed