SCHEMBL891433

SCHEMBL891433

O=C(O)[C@H](Cc1ccccc1)NO

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.59
NPSR1 Q6W5P4 1/20 0.57
CYP1A2 P05177 1/20 0.57
NAALAD2 Q9Y3Q0 2/20 0.56
FOLH1 Q04609 1/20 0.54
MMP2 P08253 4/20 0.54
MMP9 P14780 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ADAMTS4 O75173 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508136 1.00 MME (0.59) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL891432 1.00 MME (0.59) MMENPSR1CYP1A2NAALAD2FOLH1
Hydrochloric Acid SCHEMBL5691387 0.98 MME (0.57) MMENPSR1CYP1A2NAALAD2FOLH1
Valine SCHEMBL27667759 0.85 SLC1A3 (0.53) MMEMMP2MMP9L3MBTL1
SCHEMBL7379335 0.85 MME (0.70) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL157547 0.85 MME (0.61) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL9068541 0.85 MME (0.70) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL156975 0.84 FOLH1 (0.58) MMENAALAD2FOLH1L3MBTL1
SCHEMBL156976 0.84 FOLH1 (0.58) MMENAALAD2FOLH1L3MBTL1
SCHEMBL1803033 0.84 EPHX1 (0.55) MMECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4352074-A1 ANTIVIRAL LARAZOTIDE DERIVATIVES Fasano, Alessio (US) 2024-04-17 EP claimed
WO-2022259049-A1 ANTIVIRAL LARAZOTIDE DERIVATIVES FASANO ALESSIO (US) 2022-12-15 WO claimed
CN-114813557-A Quantitative detection kit for p-hydroxyphenylalanine in urine and detection method thereof 兰州大学第一医院 2022-07-29 CN claimed
CN-114716635-A Multifunctional polyurea-amino acid derivative and preparation method and application thereof 四川大学 2022-07-08 CN claimed
US-20200325190-A1 Modification and Compositions of Human Secretoglobin Proteins APC RESEARCH ASSETS, LLC 2020-10-15 US claimed
CN-211627380-U Convenient p hydroxy phenyl alanine urine detection test paper box that detects 江苏东博生物医药有限公司 2020-10-02 CN claimed
CN-211426509-U P-hydroxy phenylalanine urine detection kit with good protection performance 江苏东博生物医药有限公司 2020-09-04 CN claimed
CN-211426281-U Anti-falling p-hydroxyphenylalanine urine detection kit 江苏东博生物医药有限公司 2020-09-04 CN claimed
US-20190337999-A1 Modification and Compositions of Human Secretoglobin Proteins APC RESEARCH ASSETS, LLC 2019-11-07 US claimed
US-10294285-B2 Modification and compositions of human secretoglobin proteins CLARASSANCE, INC. 2019-05-21 US claimed
US-6949660-B2 Chiral (1pyrrolino) fullerene derivatives SETH NANOTECHNOLOGY, INCORPORATED (US) 2005-09-27 US claimed
US-6790963-B2 STEREOSPECIFIC PHOTODYANMIC THERAPY SENSITIZERS TO ENHANCE CYTOTOXICITY OF ANTITUMOR AGENTS; FULLEROPYRROLIDINE COMPOUNDS CHIANG, LONG Y. (TW) 2004-09-14 US claimed
US-20040034205-A1 Chiral (1pyrrolino) fullerene derivatives CHIANG, LONG Y. 2004-02-19 US claimed
US-20030013861-A1 E-isomeric fullerene derivatives CHIANG, LONG Y. (TW) 2003-01-16 US claimed
US-20030009036-A1 E-isomeric fullerene derivatives SETHNANOTECHNOLOGY, INCORPORATED 2003-01-09 US claimed
CN-1317484-A Fullerene derivatives of the E-isomer JIANG LONGYONG (CN) 2001-10-17 CN claimed
EP-1132380-A1 E-Isomeric fullerene derivatives Chiang, Long Y. (TW) 2001-09-12 EP claimed
EP-0836616-A1 MACROLIDES Novartis AG (CH) 1998-04-22 EP claimed
WO-1997002285-A1 MACROLIDES NOVARTIS AG (CH) 1997-01-23 WO claimed
US-4145255-A ENZYMATIC OXIDATION THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1979-03-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030013861-A1 E-isomeric fullerene derivatives PCBP1, EFNA1, DPYD MME 3759/4885NPSR1 1480/4885CYP1A2 50/4885
US-20040034205-A1 Chiral (1pyrrolino) fullerene derivatives PCBP1, RPLP1, RPLP2 MME 4813/4885NPSR1 1515/4885CYP1A2 86/4885
US-20030009036-A1 E-isomeric fullerene derivatives PCBP1, EFNA1, DPYD MME 3759/4885NPSR1 1480/4885CYP1A2 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.