SCHEMBL9508136

SCHEMBL9508136

O=C(O)[C@@H](Cc1ccccc1)NO

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.59
NPSR1 Q6W5P4 1/20 0.57
CYP1A2 P05177 1/20 0.57
NAALAD2 Q9Y3Q0 2/20 0.56
FOLH1 Q04609 1/20 0.54
MMP2 P08253 4/20 0.54
MMP9 P14780 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ADAMTS4 O75173 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891433 1.00 MME (0.59) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL891432 1.00 MME (0.59) MMENPSR1CYP1A2NAALAD2FOLH1
Hydrochloric Acid SCHEMBL5691387 0.98 MME (0.57) MMENPSR1CYP1A2NAALAD2FOLH1
Valine SCHEMBL27667759 0.85 SLC1A3 (0.53) MMEMMP2MMP9L3MBTL1
SCHEMBL7379335 0.85 MME (0.70) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL157547 0.85 MME (0.61) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL9068541 0.85 MME (0.70) MMENPSR1CYP1A2NAALAD2FOLH1
SCHEMBL156975 0.84 FOLH1 (0.58) MMENAALAD2FOLH1L3MBTL1
SCHEMBL156976 0.84 FOLH1 (0.58) MMENAALAD2FOLH1L3MBTL1
SCHEMBL1803033 0.84 EPHX1 (0.55) MMECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180193209-A1 A POLYMER PRODUCT AND PREPARATION THEROF SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2018-07-12 US claimed
EP-3319779-A1 A POLYMER PRODUCT AND PREPARATION THEREOF Singapore Health Services Pte Ltd (SG) 2018-05-16 EP claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 US disclosed
US-20230159450-A1 DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH 2023-05-25 US disclosed
US-20210299211-A1 PEPTIDOMIMETIC MACROCYCLES AND FORMULATIONS THEREOF AILERON THERAPEUTICS, INC. 2021-09-30 US disclosed
CN-111836638-A HLA class I-restricted T cell receptor for mutated RAS 美国卫生和人力服务部 2020-10-27 CN disclosed
US-20180193209-A1 A POLYMER PRODUCT AND PREPARATION THEROF SINGAPORE HEALTH SERVICES PTE LTD. (SG) 2018-07-12 US disclosed
EP-3319779-A1 A POLYMER PRODUCT AND PREPARATION THEREOF Singapore Health Services Pte Ltd (SG) 2018-05-16 EP disclosed
CN-101084248-A Macroporous plastic bead material ROEHM GMBH (DE) 2007-12-05 CN disclosed
EP-0330247-B1 N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND OTHER DERIVATIVES THEREOF DSM N.V. (NL) 1993-07-07 EP disclosed
US-5101036-A PROCESS FOR THE PREPARATION OF N-HYDROXY-ALPHA-AMINO ACID AMIDES STAMICARBON B.V. (NL) 1992-03-31 US disclosed
US-5072041-A OPTICALLY ACTIVE N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND THEIR DERIVATIVES STAMICARBON B.V. (NL) 1991-12-10 US disclosed
EP-0330247-A1 N-hydroxy-alpha-amino acids, amides and other derivatives thereof DSM N.V. (NL) 1989-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS MME 3022/4885NPSR1 139/4885CYP1A2 4402/4885
US-20210299211-A1 PEPTIDOMIMETIC MACROCYCLES AND FORMULATIONS THEREOF MDM2, TP53, TP53BP1 MME 1213/4885NPSR1 2708/4885CYP1A2 4431/4885
US-20230159450-A1 DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, DAP3, ANPEP MME 828/4885NPSR1 80/4885CYP1A2 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.