Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219148 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL2258666 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL16884944 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL1520965 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL28564447 | 0.79 | THRB (0.52) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL15382525 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL11299148 | 0.79 | ALOX15 (0.56) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL4087701 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL4513312 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTNPSR1GLO1 | |
| SCHEMBL9615000 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTNPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637719-A | PROTECTING PRIMARY OR SECONDARY AMINE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | claimed |
| EP-0401817-B1 | Reagents for rapid peptide synthesis | RES CORP TECHNOLOGIES INC (US) | 1995-09-13 | — | — | EP | claimed |
| US-5221754-A | Easily removable blocking groups to protect primary or secondary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-22 | — | — | US | claimed |
| EP-0401817-A2 | Reagents for rapid peptide synthesis | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-12 | — | — | EP | claimed |
| US-5637719-A | PROTECTING PRIMARY OR SECONDARY AMINE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5510491-A | 2-PROPENYL CHLOROFORMATE AND DERIVATIVES AS BLOCKING AGENTS FOR AMINO GROUPS OF PEPTIDES DURING PEPTIDE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0401817-B1 | Reagents for rapid peptide synthesis | RES CORP TECHNOLOGIES INC (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0496836-B1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RES CORP TECHNOLOGIES INC (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5221754-A | Easily removable blocking groups to protect primary or secondary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0496836-A4 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0496836-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS. | RES CORP TECHNOLOGIES INC (US) | 1992-08-05 | — | — | EP | disclosed |
| WO-1991005564-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |
| EP-0401817-A2 | Reagents for rapid peptide synthesis | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-12 | — | — | EP | disclosed |