Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914503 | 0.73 | CA12 (0.36) | HSP90AA1PAX8POLBGAAKMT2A | |
| SCHEMBL8918178 | 0.73 | CA12 (0.36) | HSP90AA1PAX8POLBGAAKMT2A | |
| SCHEMBL8915432 | 0.72 | ALDH1A1 (0.36) | HSP90AA1PAX8GAAKMT2AALDH1A1 | |
| SCHEMBL8916026 | 0.68 | NSD2 (0.40) | HSP90AA1PAX8KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13598135 | 0.67 | GAA (0.34) | GAAKMT2A | |
| SCHEMBL15705491 | 0.65 | — | — | |
| SCHEMBL27512581 | 0.60 | KMT2A (0.50) | POLBKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL648371 | 0.59 | L3MBTL1 (0.69) | POLBGAAKMT2AALDH1A1 | |
| SCHEMBL980002 | 0.57 | STS (0.71) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10701200 | 0.57 | MAPT (0.37) | POLBGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625059-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5312914-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORP (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0279781-A2 | Process for the preparation of 4-acetoxy-3-hydroxyethyl-acetidinone | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | disclosed |