Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113435 | 0.86 | L3MBTL1 (0.65) | L3MBTL1SLC6A3CA1CA2CA5A | |
| SCHEMBL27480641 | 0.86 | L3MBTL1 (0.69) | L3MBTL1SLC6A3CA1CA2CA5A | |
| SCHEMBL21034056 | 0.84 | L3MBTL1 (0.67) | L3MBTL1SLC6A3CA1CA2CA5A | |
| SCHEMBL8606486 | 0.83 | L3MBTL1 (0.65) | L3MBTL1SLC6A3CA1CA2CA5A | |
| SCHEMBL4731724 | 0.81 | LMNA (0.51) | L3MBTL1KMT2ATSHRLMNAHSD17B10 | |
| SCHEMBL2478066 | 0.81 | KDM4E (0.56) | L3MBTL1KMT2ATSHRLMNAHSD17B10 | |
| SCHEMBL3529817 | 0.81 | L3MBTL1 (1.00) | L3MBTL1SLC6A3CA1CA2CA5A | |
| SCHEMBL1665977 | 0.81 | MAPT (0.70) | L3MBTL1SLC6A3CA1CA2CA5A | |
| SCHEMBL14198530 | 0.81 | MAPT (0.70) | L3MBTL1SLC6A3KMT2ATSHRLMNA | |
| SCHEMBL28495110 | 0.80 | KDM4E (0.49) | L3MBTL1SLC6A3CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727524-B | Internal electron donor compound and catalyst for catalyzing propylene polymerization | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-108727524-B | Internal electron donor compound and catalyst for catalyzing propylene polymerization | 中国石油天然气股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-10407376-B2 | Method to prepare phenolics from biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2019-09-10 | — | — | US | disclosed |
| US-20180033966-A1 | NOVEL COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE COMPRISING SAME | DUK SAN NEOLUX CO., LTD. (KR) | 2018-02-01 | — | — | US | disclosed |
| US-20170349529-A1 | Method to Prepare Phenolics from Biomass | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2017-12-07 | — | — | US | disclosed |
| EP-3245186-A1 | METHOD TO PREPARE PHENOLICS FROM BIOMASS | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO (NL) | 2017-11-22 | — | — | EP | disclosed |
| WO-2016114668-A1 | METHOD TO PREPARE PHENOLICS FROM BIOMASS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2016-07-21 | — | — | WO | disclosed |
| EP-1963294-B1 | 1,2,5-THIAZOLIDINE DERIVATIVES USEFUL FOR TREATING CONDITIONS MEDIATED BY PROTEIN TYROSINE PHOSPHATASES (PTPASE) | NOVARTIS AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| US-8119666-B2 | 1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (PTPase) | NOVARTIS AG (CH) | 2012-02-21 | — | — | US | disclosed |
| US-8084448-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-12-27 | — | — | US | disclosed |
| WO-2007067613-A1 | 1,2,5-THIAZOLIDINE DERIVATIVES USEFUL FOR TREATING CONDITIONS MEDIATED BY PROTEIN TYROSINE PHOSPHATASES (PTPASE) | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |
| US-20060135582-A1 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | DIPHARMA S.P.A. (IT) | 2006-06-22 | — | — | US | disclosed |
| EP-1581508-A1 | A PROCESS FOR THE PREPARATION OF BENZO D ISOXAZOL-3-YL- METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | Dipharma S.p.A. (IT) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004063173-A1 | A PROCESS FOR THE PREPARATION OF BENZO[D]ISOXAZOL-3-YL-METHANESULFONIC ACID AND THE INTERMEDIATES THEREOF | DIPHARMA S.P.A. (IT) | 2004-07-29 | — | — | WO | disclosed |
| US-6433214-B1 | Process for the preparation of 2-(4-methylphenyl)-benzoic acid derivatives | DIPHARMA S.P.A. (IT) | 2002-08-13 | — | — | US | disclosed |
| EP-1044956-A1 | A process for the preparation of 2-(4-methylphenyl) benzoic acid derivatives | Dinamite Dipharma S.p.A. (IT) | 2000-10-18 | — | — | EP | disclosed |
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407376-B2 | Method to prepare phenolics from biomass | FDPS, DNPH1, HPD | L3MBTL1 4637/4885SLC6A3 4582/4885CA1 4426/4885 |
| US-20170349529-A1 | Method to Prepare Phenolics from Biomass | FDPS, DNPH1, HPD | L3MBTL1 4637/4885SLC6A3 4582/4885CA1 4426/4885 |
| US-20180033966-A1 | NOVEL COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING THE SAME, AND ELECTRONIC DEVICE COMPRISING SAME | EBPL, OR51E2, EML4 | L3MBTL1 1325/4885SLC6A3 4293/4885CA1 1828/4885 |
| US-20060135582-A1 | Process for the preparation of benzo [d] isoxazol-3-yl-methanesulfonic acid and the intermediates thereof | GABRD, GABRA5, GABRA6 | L3MBTL1 4876/4885SLC6A3 1858/4885CA1 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.