Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12278853 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12278267 | 0.76 | ALDH1A1 (0.37) | ALDH1A1GPR84SOAT1SMN1; SMN2 | |
| SCHEMBL16706177 | 0.72 | GPR35 (0.44) | ALDH1A1GPR35GAAHTT | |
| SCHEMBL2689776 | 0.72 | GPR35 (0.44) | ALDH1A1GPR35GAAHTT | |
| SCHEMBL12925771 | 0.72 | GPR35 (0.44) | ALDH1A1GPR35GAAHTT | |
| SCHEMBL17372958 | 0.71 | FBP1 (0.43) | ALDH1A1GPR84GAASOAT1SMN1; SMN2 | |
| SCHEMBL20669518 | 0.71 | FBP1 (0.43) | ALDH1A1GPR84GAASOAT1SMN1; SMN2 | |
| SCHEMBL5315566 | 0.71 | FBP1 (0.43) | ALDH1A1GPR84GAASOAT1SMN1; SMN2 | |
| SCHEMBL12277829 | 0.71 | ALDH1A1 (0.33) | ALDH1A1GPR84SMN1; SMN2 | |
| SCHEMBL12278245 | 0.71 | ALDH1A1 (0.33) | ALDH1A1GPR84SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684165-A | FOR USE IN NONLINEAR OPTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5432286-A | Nonlinear optics | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| EP-0592919-A1 | Substituted thieno[3,2-b]thiophenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-20 | — | — | EP | disclosed |