Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914706 | 0.83 | SMN1; SMN2 (0.49) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8917655 | 0.78 | ALDH1A1 (0.48) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8914936 | 0.76 | ALDH1A1 (0.44) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL9483696 | 0.76 | MAPT (0.40) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8914469 | 0.75 | ALDH1A1 (0.41) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8914970 | 0.72 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8914962 | 0.72 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL8914974 | 0.72 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL5187614 | 0.68 | HSD11B1 (0.52) | ALDH1A1MAPTSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL28235593 | 0.66 | HTT (0.53) | LMNAALDH1A1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637719-A | PROTECTING PRIMARY OR SECONDARY AMINE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | claimed |
| EP-0401817-B1 | Reagents for rapid peptide synthesis | RES CORP TECHNOLOGIES INC (US) | 1995-09-13 | — | — | EP | claimed |
| US-5221754-A | Easily removable blocking groups to protect primary or secondary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-22 | — | — | US | claimed |
| EP-0401817-A2 | Reagents for rapid peptide synthesis | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-12 | — | — | EP | claimed |
| US-5637719-A | PROTECTING PRIMARY OR SECONDARY AMINE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5510491-A | 2-PROPENYL CHLOROFORMATE AND DERIVATIVES AS BLOCKING AGENTS FOR AMINO GROUPS OF PEPTIDES DURING PEPTIDE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0401817-B1 | Reagents for rapid peptide synthesis | RES CORP TECHNOLOGIES INC (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0496836-B1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RES CORP TECHNOLOGIES INC (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5221754-A | Easily removable blocking groups to protect primary or secondary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0496836-A4 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0496836-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS. | RES CORP TECHNOLOGIES INC (US) | 1992-08-05 | — | — | EP | disclosed |
| WO-1991005564-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |
| EP-0401817-A2 | Reagents for rapid peptide synthesis | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-12 | — | — | EP | disclosed |