Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916021 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8914917 | 0.78 | LMNA (0.42) | ALDH1A1SMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL8914895 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8914898 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8914893 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL6376610 | 0.73 | L3MBTL1 (0.54) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL9483696 | 0.70 | MAPT (0.40) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL3795024 | 0.69 | POLB (0.68) | ALDH1A1SMN1; SMN2KMT2AMEN1CYP1A2 | |
| SCHEMBL8339054 | 0.67 | NPSR1 (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8914469 | 0.67 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637719-A | PROTECTING PRIMARY OR SECONDARY AMINE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5510491-A | 2-PROPENYL CHLOROFORMATE AND DERIVATIVES AS BLOCKING AGENTS FOR AMINO GROUPS OF PEPTIDES DURING PEPTIDE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0401817-B1 | Reagents for rapid peptide synthesis | RES CORP TECHNOLOGIES INC (US) | 1995-09-13 | — | — | EP | disclosed |
| EP-0496836-B1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | RES CORP TECHNOLOGIES INC (US) | 1995-06-14 | — | — | EP | disclosed |
| US-5221754-A | Easily removable blocking groups to protect primary or secondary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-22 | — | — | US | disclosed |