Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916232 | 0.81 | ALDH1A1 (0.46) | KDM4ELMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL8915432 | 0.80 | ALDH1A1 (0.36) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL13486531 | 0.79 | LMNA (0.43) | KDM4ELMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL13486541 | 0.77 | LMNA (0.45) | KDM4ELMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL8915454 | 0.74 | GLA (0.40) | KDM4ELMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL13486543 | 0.74 | KDM4E (0.39) | KDM4ELMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL17603301 | 0.66 | TSHR (0.53) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL17603302 | 0.66 | TSHR (0.53) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL11669385 | 0.66 | KDM4E (0.67) | KDM4ELMNAALDH1A1HTTHSD17B10 | |
| Urethane SCHEMBL844947 | 0.66 | ALOX15 (0.58) | KDM4ELMNAALDH1A1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625059-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5312914-A | Process for the manufacture of 4-acetoxy-3-hydroxyethyl-azetidinone | CIBA-GEIGY CORP (US) | 1994-05-17 | — | — | US | disclosed |
| EP-0279781-A2 | Process for the preparation of 4-acetoxy-3-hydroxyethyl-acetidinone | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | disclosed |