SCHEMBL8914980

SCHEMBL8914980

CSc1sc2c(C)csc2c1C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.35
HPGD P15428 1/20 0.31
PDPK1 O15530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13407285 0.73 GPR35 (0.39) GPR35PDPK1
SCHEMBL18876130 0.73 GPR35 (0.39) GPR35PDPK1
SCHEMBL12704397 0.71 GPR35 (0.48) GPR35PDPK1
SCHEMBL13407286 0.71 GPR35 (0.38) GPR35PDPK1
SCHEMBL13407290 0.71 GPR35 (0.38) GPR35PDPK1
SCHEMBL22242113 0.70
SCHEMBL24445358 0.70 GPR35 (0.37) GPR35PDPK1
SCHEMBL18876167 0.70 GPR35 (0.37) GPR35PDPK1
SCHEMBL18876194 0.70 GPR35 (0.41) GPR35PDPK1
SCHEMBL18876240 0.70 GPR35 (0.37) GPR35PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684165-A FOR USE IN NONLINEAR OPTICS HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-04 US disclosed
US-5432286-A Nonlinear optics HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-11 US disclosed
EP-0592919-A1 Substituted thieno[3,2-b]thiophenes and their use HOECHST AKTIENGESELLSCHAFT (DE) 1994-04-20 EP disclosed