Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407290 | 1.00 | GPR35 (0.38) | GPR35PDPK1 | |
| SCHEMBL13407285 | 0.98 | GPR35 (0.39) | GPR35PDPK1 | |
| SCHEMBL18876130 | 0.78 | GPR35 (0.39) | GPR35PDPK1 | |
| SCHEMBL12704397 | 0.76 | GPR35 (0.48) | GPR35PDPK1 | |
| SCHEMBL13711894 | 0.75 | GPR35 (0.46) | GPR35 | |
| SCHEMBL18876194 | 0.74 | GPR35 (0.41) | GPR35PDPK1 | |
| SCHEMBL18876167 | 0.74 | GPR35 (0.37) | GPR35PDPK1 | |
| SCHEMBL18876240 | 0.74 | GPR35 (0.37) | GPR35PDPK1 | |
| SCHEMBL15297608 | 0.74 | GPR35 (0.47) | GPR35PDPK1 | |
| SCHEMBL12704373 | 0.74 | GPR35 (0.47) | GPR35PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700643-B2 | Polymerisable thieno[3,2-b]thiophenes | MERCK PATENT GMBH (DE) | 2010-04-20 | — | — | US | disclosed |
| US-7700643-B2 | Polymerisable thieno[3,2-b]thiophenes | MERCK PATENT GMBH (DE) | 2010-04-20 | — | — | US | disclosed |
| US-20070246704-A1 | Polymerisable ThienO[3,2-B]Thiophenes | MERCK PATENT GMBH (DE) | 2007-10-25 | — | — | US | disclosed |
| US-20070246704-A1 | Polymerisable ThienO[3,2-B]Thiophenes | MERCK PATENT GMBH (DE) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070246704-A1 | Polymerisable ThienO[3,2-B]Thiophenes | TPR, OR10J3, FTO | GPR35 2932/4885PDPK1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.