Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12704373 | 0.97 | GPR35 (0.47) | GPR35PDPK1 | |
| SCHEMBL15297608 | 0.97 | GPR35 (0.47) | GPR35PDPK1 | |
| SCHEMBL1413229 | 0.83 | GPR35 (0.39) | GPR35PDPK1 | |
| SCHEMBL18031643 | 0.82 | GPR35 (0.42) | GPR35PDPK1 | |
| SCHEMBL18950178 | 0.78 | GPR35 (0.56) | GPR35 | |
| SCHEMBL18876130 | 0.78 | GPR35 (0.39) | GPR35PDPK1 | |
| SCHEMBL13407285 | 0.78 | GPR35 (0.39) | GPR35PDPK1 | |
| SCHEMBL6462702 | 0.77 | GPR35 (0.46) | GPR35 | |
| SCHEMBL13407290 | 0.76 | GPR35 (0.38) | GPR35PDPK1 | |
| SCHEMBL13407286 | 0.76 | GPR35 (0.38) | GPR35PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160369045-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | CORNING INC (US) | 2016-12-22 | — | — | US | disclosed |
| EP-2773646-B1 | CONJUGATED FUSED THIOPHENES, METHODS OF MAKING CONJUGATED FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2129678-B1 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF | CORNING INC (US) | 2015-05-27 | — | — | EP | disclosed |
| US-20150065722-A1 | FUSED THIOPHENE DITIN MONOMERS | CORNING INCORPORATED | 2015-03-05 | — | — | US | disclosed |
| US-20150045560-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | CORNING INCORPORATED | 2015-02-12 | — | — | US | disclosed |
| EP-2308882-A1 | Fused thiophenes and uses thereof | Corning Incorporated (US) | 2011-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065722-A1 | FUSED THIOPHENE DITIN MONOMERS | TTL, THEM6, ITK | GPR35 4686/4885PDPK1 779/4885 |
| US-20150045560-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | FDPS, PPOX, DHPS | GPR35 4268/4885PDPK1 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.