Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | ACP1 | P24666 | 3/20 | 0.37 |
| ▸ | CDC25B | P30305 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565195 | 0.76 | TDP1 (0.43) | TDP1L3MBTL1PPARGMAPTMEN1 | |
| SCHEMBL7140999 | 0.74 | CPT1A (0.34) | TDP1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL3752952 | 0.67 | TDP1 (0.41) | TDP1L3MBTL1PPARGMAPTPTPN1 | |
| SCHEMBL7153573 | 0.67 | PTPN1 (0.39) | ACHEBACE1PTPN1CDC25BGPR84 | |
| SCHEMBL3239526 | 0.66 | ACHE (0.43) | TDP1L3MBTL1PPARGACHEBACE1 | |
| SCHEMBL861873 | 0.64 | — | — | |
| SCHEMBL11156027 | 0.63 | ACHE (0.37) | TDP1MAPTMEN1KMT2AACHE | |
| SCHEMBL1468241 | 0.63 | ACHE (0.37) | TDP1MAPTMEN1KMT2AACHE | |
| SCHEMBL7142903 | 0.63 | CDC25B (0.37) | TDP1PPARGMAPTMEN1KMT2A | |
| SCHEMBL2550550 | 0.62 | TSHR (0.42) | MAPTMEN1KMT2AACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5648550-A | Beta-keto-alcohols and the process for the manufacture thereof | ROCHE VITAMINS INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |