Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 10/20 | 0.40 |
| ▸ | CDC25A | P30304 | 7/20 | 0.40 |
| ▸ | CDC25C | P30307 | 6/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | ACP1 | P24666 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937204 | 0.78 | PTGS2 (0.32) | — | |
| SCHEMBL7142903 | 0.70 | CDC25B (0.37) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL9941221 | 0.70 | CDC25A (0.55) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL82554 | 0.69 | CDC25A (0.69) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL3743037 | 0.68 | — | — | |
| SCHEMBL11176370 | 0.67 | CDC25A (0.72) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL17706772 | 0.67 | CDC25A (0.72) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL9631357 | 0.67 | CDC25A (0.72) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL6243699 | 0.67 | CDC25A (0.72) | TDP1ALDH1A1MAPTTHRBCDC25B | |
| SCHEMBL6242255 | 0.67 | CDC25A (0.72) | TDP1ALDH1A1MAPTTHRBCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046147-B1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-01 | — | — | EP | claimed |
| US-20090311403-A1 | Method of Using Organic Compounds | GIVAUDAN SA (CH) | 2009-12-17 | — | — | US | claimed |
| CN-101494999-A | Method for using organic compound | GIVAUDAN SA (CH) | 2009-07-29 | — | — | CN | claimed |
| EP-2046147-A1 | METHOD OF USING ORGANIC COMPOUNDS | Givaudan SA (CH) | 2009-04-15 | — | — | EP | claimed |
| WO-2008011742-A1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-01-31 | — | — | WO | claimed |
| EP-2046147-B1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
| US-20090311403-A1 | Method of Using Organic Compounds | GIVAUDAN SA (CH) | 2009-12-17 | — | — | US | disclosed |
| CN-101494999-A | Method for using organic compound | GIVAUDAN SA (CH) | 2009-07-29 | — | — | CN | disclosed |
| EP-2046147-A1 | METHOD OF USING ORGANIC COMPOUNDS | Givaudan SA (CH) | 2009-04-15 | — | — | EP | disclosed |
| EP-1996569-A1 | FLAVORANT AND FRAGRANCE COMPOUNDS | Givaudan SA (CH) | 2008-12-03 | — | — | EP | disclosed |
| WO-2008011742-A1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-01-31 | — | — | WO | disclosed |
| WO-2007107023-A1 | FLAVORANT AND FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107023-A1 | FLAVORANT AND FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090311403-A1 | Method of Using Organic Compounds | MGLL, GK, LIPC | TDP1 3828/4885ALDH1A1 788/4885MAPT 2208/4885 |
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | TAS2R5, TAS2R1, TAS1R1 | TDP1 3583/4885ALDH1A1 106/4885MAPT 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.