Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 8/20 | 0.37 |
| ▸ | CDC25A | P30304 | 6/20 | 0.37 |
| ▸ | CDC25C | P30307 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.33 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752952 | 0.70 | TDP1 (0.41) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL505901 | 0.65 | ALDH1A1 (0.46) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL82554 | 0.65 | CDC25A (0.69) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL4281978 | 0.64 | ALDH1A1 (0.36) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL2983601 | 0.64 | ALOX5 (0.45) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL3899938 | 0.64 | DUSP3 (0.40) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL9631357 | 0.63 | CDC25A (0.72) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL11176370 | 0.63 | CDC25A (0.72) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL17706772 | 0.63 | CDC25A (0.72) | CDC25BCDC25ACDC25CALDH1A1MAPT | |
| SCHEMBL28642404 | 0.63 | ALDH1A1 (0.48) | CDC25BCDC25ACDC25CALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-A1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-27 | — | — | EP | claimed |
| WO-2000061571-A1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-10-19 | — | — | WO | claimed |