Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866383 | 0.87 | MAPK1 (0.36) | LMNAMAPK1SMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL8915962 | 0.87 | MAPK1 (0.36) | LMNAMAPK1ALDH1A1PKMHPGD | |
| SCHEMBL8914864 | 0.87 | MAPK1 (0.36) | LMNAMAPK1ALDH1A1PKMHPGD | |
| SCHEMBL8914444 | 0.87 | MAPK1 (0.36) | LMNAMAPK1ALDH1A1PKMHPGD | |
| SCHEMBL6869261 | 0.86 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL6867918 | 0.82 | NPC1 (0.33) | LMNAMAPK1NPC1RAB9ANPSR1 | |
| SCHEMBL7005383 | 0.82 | ALDH1A1 (0.35) | MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7011575 | 0.79 | CA2 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL6869777 | 0.78 | GSTP1 (0.35) | ALDH1A1L3MBTL1 | |
| SCHEMBL6871755 | 0.77 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0729957-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |