Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914444 | 1.00 | MAPK1 (0.36) | MAPK1HSD17B10ALOX15POLBTDP1 | |
| SCHEMBL8915962 | 1.00 | MAPK1 (0.36) | MAPK1HSD17B10ALOX15POLBTDP1 | |
| SCHEMBL6866383 | 0.92 | MAPK1 (0.36) | MAPK1TDP1LMNAHTTNPSR1 | |
| SCHEMBL6869261 | 0.88 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL8915085 | 0.87 | LMNA (0.33) | MAPK1HSD17B10LMNANPSR1ALDH1A1 | |
| SCHEMBL6867918 | 0.86 | NPC1 (0.33) | MAPK1TDP1LMNAHTTNPSR1 | |
| SCHEMBL7005383 | 0.81 | ALDH1A1 (0.35) | MAPK1ALDH1A1KDM4EDYRK1A | |
| SCHEMBL7011575 | 0.78 | CA2 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6866392 | 0.77 | MAPK1 (0.36) | MAPK1TDP1LMNAHTTNPSR1 | |
| SCHEMBL6869777 | 0.77 | GSTP1 (0.35) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0729957-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |