Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17087191 | 0.89 | HSD17B10 (0.61) | FFAR1ALDH1A1NR1H4 | |
| SCHEMBL30593881 | 0.86 | F2RL1 (0.52) | FFAR1FFAR4 | |
| SCHEMBL13347939 | 0.84 | ALDH1A1 (0.59) | FFAR1FFAR4ALDH1A1NR1H4 | |
| SCHEMBL5652618 | 0.83 | FFAR1 (0.63) | FFAR1FFAR4KEAP1ALDH1A1NR1H4 | |
| SCHEMBL69746 | 0.82 | FFAR1 (0.81) | FFAR1FFAR4KEAP1CA1CA2 | |
| SCHEMBL10760567 | 0.82 | ALDH1A1 (0.53) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL597578 | 0.81 | IDO1 (0.52) | FFAR1ALDH1A1 | |
| SCHEMBL659263 | 0.81 | NR1H4 (0.59) | FFAR1FFAR4KEAP1ALDH1A1NR1H4 | |
| SCHEMBL11135027 | 0.80 | TSHR (0.61) | FFAR1FFAR4NR1H4 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.80 | FFAR1 (0.77) | FFAR1FFAR4KEAP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220047724-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | CYANAGEN S R L (IT) | 2022-02-17 | — | — | US | disclosed |
| US-11179481-B2 | Tricarbocyanine-cyclodextrin(s) conjugates and use thereof | CYANAGEN S.R.L. (IT) | 2021-11-23 | — | — | US | disclosed |
| EP-3305900-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2021-07-21 | — | — | EP | disclosed |
| EP-2480247-B1 | NOVEL NPR-B AGONISTS | SHIRE ORPHAN THERAPIES GMBH (DE) | 2020-02-12 | — | — | EP | disclosed |
| US-10441666-B2 | Tricarbocyanine-cyclodextrin(s) conjugates and use thereof | CYANAGEN S.R.L. (IT) | 2019-10-15 | — | — | US | disclosed |
| US-9321766-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160096832-A1 | KINASE INHIBITORS | ALLERGAN, INC. | 2016-04-07 | — | — | US | disclosed |
| US-20150328342-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | CYANAGEN S.R.L. (IT) | 2015-11-19 | — | — | US | disclosed |
| US-20150328342-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | CYANAGEN S.R.L. (IT) | 2015-11-19 | — | — | US | disclosed |
| EP-2944326-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | Cyanagen Srl (IT) | 2015-11-18 | — | — | EP | disclosed |
| US-20120238750-A1 | AROMATIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-09-20 | — | — | US | disclosed |
| US-8236826-B2 | Diarylether derivatives as antitumor agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8236826-B2 | Diarylether derivatives as antitumor agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8188277-B2 | Aromatic compounds for suppressing the generation of collagen | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8188277-B2 | Aromatic compounds for suppressing the generation of collagen | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-05-29 | — | — | US | disclosed |
| WO-2010123996-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | IMMUNOLIGHT, LLC (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20100004438-A1 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20100004438-A1 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10441666-B2 | Tricarbocyanine-cyclodextrin(s) conjugates and use thereof | KRTCAP2, DSC1, TBCD | FFAR1 3628/4885FFAR4 3102/4885KEAP1 1796/4885 |
| US-20120238750-A1 | AROMATIC COMPOUND | CBR1, CBR3, CYP1A1 | FFAR1 1263/4885FFAR4 2593/4885KEAP1 364/4885 |
| US-20220047724-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | KRTCAP2, DSC1, TBCD | FFAR1 3805/4885FFAR4 3387/4885KEAP1 1448/4885 |
| US-20150328342-A1 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF | KRTCAP2, DSC1, TBCD | FFAR1 3707/4885FFAR4 3205/4885KEAP1 1591/4885 |
| US-11179481-B2 | Tricarbocyanine-cyclodextrin(s) conjugates and use thereof | KRTCAP2, DSC1, TBCD | FFAR1 3628/4885FFAR4 3102/4885KEAP1 1796/4885 |
| US-20100004438-A1 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | ROS1, CBR1, CBR3 | FFAR1 865/4885FFAR4 2072/4885KEAP1 113/4885 |
| US-20160096832-A1 | KINASE INHIBITORS | ABL1, LCK, ERBB2 | FFAR1 3540/4885FFAR4 4263/4885KEAP1 1734/4885 |
| US-20070270422-A1 | Aromatic Compounds | COL1A1, COL2A1, COL14A1 | FFAR1 1139/4885FFAR4 1833/4885KEAP1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.