SCHEMBL8915293

SCHEMBL8915293

Cc1cc(-c2ccc(Oc3ccc(N)cc3)cc2)ccc1Oc1ccc(N)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
TEAD4 Q15561 1/20 0.52
MAPT P10636 6/20 0.50
TDP1 Q9NUW8 4/20 0.50
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.50
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MITF O75030 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
NLRP1 Q9C000 1/20 0.46
NOD2 Q9HC29 1/20 0.46
MAOA P21397 2/20 0.44
HPGD P15428 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020707 0.96 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL2989217 0.89 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL1810759 0.87 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL29510593 0.87 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL6935710 0.85 MAOB (0.54) ALDH1A1SMN1; SMN2MAPTCYP3A4POLB
SCHEMBL1155719 0.85 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL3003478 0.85 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL29688467 0.85 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL31457276 0.85 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL28551523 0.85 MAPT (0.51) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257621-A1 METHOD FOR PRODUCING PATTERNED SUBSTRATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-11 EP disclosed
US-5650463-A Carbon fiber-reinforced polimide resin composition MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-22 US disclosed
US-5554765-A HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-10 US disclosed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP disclosed
US-5457154-A Melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1995-10-10 US disclosed
EP-0523240-A1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed