Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855350 | 1.00 | RAPGEF4 (0.41) | RAPGEF4NOTUMPGK1PGK2HSD11B1 | |
| SCHEMBL10983557 | 0.88 | CD44 (0.41) | RAPGEF4NOTUMPGK1PGK2HSD11B1 | |
| SCHEMBL25789703 | 0.84 | RAPGEF4 (0.38) | RAPGEF4NOTUMPGK1PGK2HSD11B1 | |
| SCHEMBL9243570 | 0.84 | RAPGEF4 (0.38) | RAPGEF4NOTUMPGK1PGK2HSD11B1 | |
| SCHEMBL10493649 | 0.83 | RAPGEF4 (0.43) | RAPGEF4NOTUMIDO1HTR3EHTR3B | |
| SCHEMBL27373921 | 0.82 | CD44 (0.46) | RAPGEF4IDO1HTR3EHTR3BHTR3A | |
| SCHEMBL10293004 | 0.81 | PGK1 (0.41) | RAPGEF4NOTUMPGK1PGK2S1PR1 | |
| SCHEMBL13568683 | 0.80 | RAPGEF4 (0.44) | RAPGEF4NOTUMHSD11B1IDO1HTR3E | |
| SCHEMBL15958047 | 0.78 | PGK1 (0.50) | RAPGEF4NOTUMPGK1PGK2HSD11B1 | |
| SCHEMBL18179221 | 0.78 | AR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886700-A | Preparation method of 2-methyl-3-trifluoromethyl aniline | 福建永晶科技股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| JP-63045241-A | — | — | None | — | — | JP | disclosed |
| JP-63270632-A | — | — | None | — | — | JP | disclosed |
| JP-63045240-A | — | — | None | — | — | JP | disclosed |
| CN-117886700-A | Preparation method of 2-methyl-3-trifluoromethyl aniline | 福建永晶科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-11040954-B1 | CXCR3 receptor agonists | RECEPTOS LLC (US) | 2021-06-22 | — | — | US | disclosed |
| US-20190345133-A1 | CXCR3 RECEPTOR AGONISTS | RECEPTOS LLC | 2019-11-14 | — | — | US | disclosed |
| CN-1935758-A | Process for producing 2-methyl-4,5-dichloro benzo trifluoride | SHU YUANAN (CN) | 2007-03-28 | — | — | CN | disclosed |
| US-5600036-A | 2-trifluoromethyl-4-chlorobenzalchloride and 2-methyl-3-nitro-5-chlorobenzotrifluoride useful as intermediates for preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5449831-A | Process of preparing 2-methyl-3-aminobenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1995-09-12 | — | — | US | disclosed |
| US-4876404-A | Preparation of dichlorotrifluoromethyltoluenes including novel isomers | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4876404-A | Preparation of dichlorotrifluoromethyltoluenes including novel isomers | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | disclosed |
| JP-S63270632-A | NOVEL DICHLOROTRIFLUOROMETHYLTOLUENE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-11-08 | — | — | JP | disclosed |
| JP-S6345241-A | PRODUCTION OF 2-METHYL-3-AMINO-BENZOTRIFLUORIDE | CENTRAL GLASS CO LTD | 1988-02-26 | — | — | JP | disclosed |
| JP-S6345240-A | 3,4-DICHLORO-6-TRIFLUOROMETHYL-TOLUENE DERIVATIVE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-02-26 | — | — | JP | disclosed |
| US-4533777-A | HALOALKYLATION OF A BENZENE RING USING CARBON TETRACHLORIDE AND HYDROFLUORIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-06 | — | — | US | disclosed |
| EP-0008453-B1 | PROCESS FOR PREPARING TRIFLUOROMETHYL AROMATIC COMPOUNDS | BAYER AG (DE) | 1981-04-29 | — | — | EP | disclosed |
| EP-0008453-A1 | Process for preparing trifluoromethyl aromatic compounds | BAYER AG (DE) | 1980-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040954-B1 | CXCR3 receptor agonists | CXCR3, CXCR1, CCR7 | RAPGEF4 1287/4885NOTUM 4696/4885PGK1 3865/4885 |
| US-20190345133-A1 | CXCR3 RECEPTOR AGONISTS | CXCR3, CXCR1, CCR7 | RAPGEF4 1287/4885NOTUM 4696/4885PGK1 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.