Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286616 | 0.83 | GAA (0.45) | GAAALDH1A1GFERSMN1; SMN2L3MBTL1 | |
| SCHEMBL8772047 | 0.81 | ICMT (0.32) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22655985 | 0.74 | SMN1; SMN2 (0.44) | GAAALDH1A1GFERSMN1; SMN2L3MBTL1 | |
| SCHEMBL8914214 | 0.73 | SMN1; SMN2 (0.51) | GAASMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL9985451 | 0.72 | SMN1; SMN2 (0.56) | GAAALDH1A1GFERSMN1; SMN2L3MBTL1 | |
| SCHEMBL5734658 | 0.69 | ALDH1A1 (0.69) | GAAALDH1A1GFERSMN1; SMN2CYP4F2 | |
| SCHEMBL5957236 | 0.69 | ALDH1A1 (0.64) | GAAALDH1A1GFERSMN1; SMN2CYP4F2 | |
| SCHEMBL1457038 | 0.69 | SMN1; SMN2 (0.50) | GAAALDH1A1SMN1; SMN2L3MBTL1CYP4F2 | |
| SCHEMBL7714693 | 0.69 | GAA (0.44) | GAAALDH1A1GFERSMN1; SMN2L3MBTL1 | |
| SCHEMBL30192992 | 0.69 | ALDH1A1 (0.64) | GAAALDH1A1GFERSMN1; SMN2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686492-A | NMR DIAGNOSTIC AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | disclosed |