SCHEMBL8915552

SCHEMBL8915552

C[SiH](C)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
TSHR P16473 3/20 0.38
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SRD5A2 P31213 3/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CES2 O00748 3/20 0.32
CES1 P23141 3/20 0.32
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
TYR P14679 1/20 0.32
DRD1 P21728 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8914727 0.80 TSHR (0.63) ALDH1A1TSHRTP53ALOX15SMN1; SMN2
SCHEMBL15873969 0.80 SRD5A2 (0.55) ALDH1A1TSHRTP53SRD5A2HPGD
SCHEMBL68148 0.79 ALDH1A1 (0.59) ALDH1A1TSHRTP53ALOX15SRD5A2
SCHEMBL20587670 0.79 ALDH1A1 (0.59) ALDH1A1TSHRTP53ALOX15SRD5A2
SCHEMBL19194632 0.78 HPGD (0.56) ALDH1A1SMN1; SMN2HPGDLMNAL3MBTL1
SCHEMBL28786362 0.76 PARP10 (0.50) ALDH1A1TSHRLMNAL3MBTL1CA1
SCHEMBL6758498 0.76 ALDH1A1 (0.64) ALDH1A1TSHRTP53ALOX15SRD5A2
Hydrochloric Acid SCHEMBL2362644 0.76 ALDH1A1 (0.56) ALDH1A1TSHRTP53ALOX15SRD5A2
Ammonia Solution, Strong SCHEMBL2023211 0.76 ALDH1A1 (0.56) ALDH1A1TSHRTP53ALOX15SRD5A2
SCHEMBL28787222 0.76 ALDH1A1 (0.56) ALDH1A1TSHRTP53ALOX15SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116426197-B Wear-resistant epoxy paint and preparation process thereof 安徽众博新材料有限公司 2024-06-11 CN claimed
CN-116426197-A Wear-resistant epoxy paint and preparation process thereof 安徽众博新材料有限公司 2023-07-14 CN claimed
EP-0304720-B1 DIMETHYLSILYL SUBSTITUTED BENZOYLCHLORIDES AND PROCESS FOR THEIR PREPARATION Consortium für elektrochemische Industrie GmbH (DE) 1991-06-26 EP claimed
US-4914221-A Dimethylsilyl-substituted benzoyl chlorides and a process for preparing the same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1990-04-03 US claimed
EP-0304720-A1 Dimethylsilyl substituted benzoylchlorides and process for their preparation Consortium für elektrochemische Industrie GmbH (DE) 1989-03-01 EP claimed
JP-1070497-A None JP disclosed
CN-116426197-B Wear-resistant epoxy paint and preparation process thereof 安徽众博新材料有限公司 2024-06-11 CN disclosed
CN-116426197-B Wear-resistant epoxy paint and preparation process thereof 安徽众博新材料有限公司 2024-06-11 CN disclosed
CN-116426197-A Wear-resistant epoxy paint and preparation process thereof 安徽众博新材料有限公司 2023-07-14 CN disclosed
CN-116426197-A Wear-resistant epoxy paint and preparation process thereof 安徽众博新材料有限公司 2023-07-14 CN disclosed
US-RE35462-E Silylated benzoic acid derivatives CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) 1997-02-25 US disclosed
US-5277838-A Silylated benzoic acid derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-01-11 US disclosed
US-5106530-A Liquid crystals Consortium Fur Elektrochemische Ind. (DE) 1992-04-21 US disclosed
EP-0304720-B1 DIMETHYLSILYL SUBSTITUTED BENZOYLCHLORIDES AND PROCESS FOR THEIR PREPARATION Consortium für elektrochemische Industrie GmbH (DE) 1991-06-26 EP disclosed
US-4914221-A Dimethylsilyl-substituted benzoyl chlorides and a process for preparing the same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1990-04-03 US disclosed
EP-0304720-A1 Dimethylsilyl substituted benzoylchlorides and process for their preparation Consortium für elektrochemische Industrie GmbH (DE) 1989-03-01 EP disclosed
EP-0304720-A1 Dimethylsilyl substituted benzoylchlorides and process for their preparation Consortium für elektrochemische Industrie GmbH (DE) 1989-03-01 EP disclosed
EP-0291778-A1 Process for the preparation of high temperature-resistant dielectrics SIEMENS AKTIENGESELLSCHAFT (DE) 1988-11-23 EP disclosed