Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | OSBP | P22059 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916895 | 0.96 | POLA1 (0.39) | PLA2G2APOLA1CYP46A1NPC1NPC1L1 | |
| SCHEMBL8912961 | 0.88 | PLA2G2A (0.45) | PLA2G2APOLA1CYP46A1NPC1NPC1L1 | |
| SCHEMBL8917330 | 0.87 | POLA1 (0.43) | PLA2G2APOLA1CYP46A1NPC1NPC1L1 | |
| SCHEMBL8915847 | 0.85 | PLA2G2A (0.41) | PLA2G2APOLA1CYP46A1NPC1NPC1L1 | |
| SCHEMBL7710522 | 0.78 | SLC29A1 (0.40) | — | |
| SCHEMBL7615989 | 0.77 | SLC29A1 (0.52) | — | |
| SCHEMBL7619002 | 0.77 | SLC29A1 (0.52) | — | |
| SCHEMBL8914132 | 0.77 | SLC29A1 (0.43) | — | |
| SCHEMBL8913660 | 0.76 | POLA1 (0.50) | PLA2G2APOLA1CYP46A1NPC1NPC1L1 | |
| SCHEMBL8912999 | 0.75 | SLC29A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643889-A | Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF PENNSYLVANIA (US) | 1997-07-01 | — | — | US | disclosed |