Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917179 | 0.90 | DRD2 (0.40) | DRD2SLC6A4HTR2AHTR1ADRD3 | |
| SCHEMBL8917070 | 0.89 | DRD2 (0.51) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8918049 | 0.85 | DRD2 (0.42) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL8916973 | 0.85 | DRD2 (0.40) | DRD2SLC6A4HTR2AHTR1ADRD3 | |
| SCHEMBL8919178 | 0.84 | HTR1A (0.41) | DRD2SLC6A4HTR2AHTR1AADRA1D | |
| SCHEMBL8917040 | 0.84 | ACHE (0.59) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL8917974 | 0.82 | DRD2 (0.38) | DRD2SLC6A4ACHEHTR2AHTR1A | |
| SCHEMBL8917024 | 0.81 | DRD2 (0.41) | DRD2SLC6A4HTR2AHTR1ADRD3 | |
| SCHEMBL8918187 | 0.81 | DRD2 (0.39) | DRD2SLC6A4HTR2AHTR1ADRD3 | |
| SCHEMBL8916899 | 0.79 | HTR1A (0.41) | DRD2SLC6A4HTR2AHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |