Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917894 | 0.84 | HTR2C (0.38) | HTR2CEPHX2HRH3 | |
| SCHEMBL4826186 | 0.84 | PRKCQ (0.41) | HRH3PRKCAPRKCQPRKCD | |
| SCHEMBL27786900 | 0.82 | ALDH1A1 (0.39) | HTR2CEPHX2 | |
| SCHEMBL8916060 | 0.82 | PRKD1 (0.40) | HTR2CEPHX2HRH3 | |
| SCHEMBL8916074 | 0.80 | HRH4 (0.39) | HTR2CEPHX2HRH3 | |
| SCHEMBL8916801 | 0.80 | ATR (0.37) | HTR2CEPHX2HRH3 | |
| SCHEMBL8916435 | 0.79 | ATR (0.36) | HTR2CEPHX2 | |
| SCHEMBL8915723 | 0.78 | ATR (0.36) | HTR2CHRH3 | |
| SCHEMBL6261311 | 0.75 | ATR (0.43) | — | |
| SCHEMBL15415762 | 0.75 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |