Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915723 | 0.90 | ATR (0.36) | PRKD1PRKD2ATRHTR6HTR2C | |
| SCHEMBL8916801 | 0.83 | ATR (0.37) | ATRHTR2CALDH1A1HRH4HRH3 | |
| SCHEMBL8916074 | 0.83 | HRH4 (0.39) | PRKD1PRKD2ATRHTR2CALDH1A1 | |
| SCHEMBL8916435 | 0.82 | ATR (0.36) | ATRHTR2CALDH1A1HRH4EPHX2 | |
| SCHEMBL8915788 | 0.82 | HTR2C (0.40) | HTR2CHRH3EPHX2 | |
| SCHEMBL8917894 | 0.81 | HTR2C (0.38) | HTR6HTR2CHRH4HRH3EPHX2 | |
| SCHEMBL27786900 | 0.77 | ALDH1A1 (0.39) | HTR2CALDH1A1EPHX2 | |
| SCHEMBL8917059 | 0.74 | PRKD1 (0.36) | PRKD1PRKD2ALDH1A1HRH4HRH3 | |
| SCHEMBL4826186 | 0.74 | PRKCQ (0.41) | ATRHRH4HRH3ADRA1AADRA1B | |
| SCHEMBL4738517 | 0.70 | ADRA1A (0.36) | HRH4ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |