Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133 | 0.81 | RECQL (0.42) | ALDH1A1TDP1LMNAMAPTGAA | |
| SCHEMBL2153555 | 0.77 | MEN1 (0.50) | ALDH1A1TDP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2153552 | 0.77 | MEN1 (0.50) | ALDH1A1TDP1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9165418 | 0.75 | ALOX15 (0.56) | ALDH1A1TDP1CYSLTR2CYSLTR1BCL9 | |
| SCHEMBL9172769 | 0.75 | ALOX15 (0.56) | ALDH1A1TDP1CYSLTR2CYSLTR1BCL9 | |
| SCHEMBL9170870 | 0.75 | ALOX15 (0.56) | ALDH1A1TDP1CYSLTR2CYSLTR1BCL9 | |
| SCHEMBL24776 | 0.75 | NR1H4 (0.41) | ALDH1A1TDP1LMNAMAPTTBXA2R | |
| SCHEMBL27988647 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TDP1CYSLTR2CYSLTR1BCL9 | |
| SCHEMBL9211218 | 0.74 | MGLL (0.38) | ALDH1A1CYSLTR2CYSLTR1LMNAMGLL | |
| SCHEMBL17048086 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TDP1CYSLTR2CYSLTR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | disclosed |
| WO-1996018605-A1 | ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |