Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917246 | 0.92 | TAAR1 (0.39) | TAAR1NPC1RAB9AL3MBTL1CYP2C9 | |
| SCHEMBL11314534 | 0.84 | L3MBTL1 (0.46) | TAAR1NPC1RAB9AL3MBTL1CYP2C9 | |
| SCHEMBL4863794 | 0.77 | NPC1 (0.57) | NPC1RAB9AL3MBTL1CYP2C9HPGD | |
| SCHEMBL24105617 | 0.75 | L3MBTL1 (0.42) | TAAR1NPC1RAB9AL3MBTL1CYP2C9 | |
| SCHEMBL646103 | 0.74 | ABL1 (0.47) | TAAR1NPC1RAB9ACYP2C9SLC5A2 | |
| SCHEMBL9024874 | 0.74 | HPGD (0.54) | TAAR1NPC1RAB9AL3MBTL1CYP2C9 | |
| SCHEMBL28468257 | 0.74 | MEN1 (0.46) | TAAR1RAB9ACYP2C9PTGS1PTGS2 | |
| SCHEMBL7025724 | 0.74 | MEN1 (0.49) | TAAR1RAB9ACYP2C9PTGS1PTGS2 | |
| SCHEMBL3456460 | 0.71 | HPGD (0.44) | TAAR1CYP2C9PTGS1PTGS2HPGD | |
| SCHEMBL4084648 | 0.71 | PTGS1 (0.57) | TAAR1L3MBTL1PTGS1PTGS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719771-A1 | Process for the preparation of methylene compounds and the compound 2-(2',4'-dichloro-5'-fluorobenzyl)-thiophene | BAYER AG (DE) | 1996-07-03 | — | — | EP | claimed |
| US-5591869-A | Process for the preparation of methylene compounds and the novel compound 2-(2,4-Dichloro-5-fluorobenzyl)thiophene | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0719771-A1 | Process for the preparation of methylene compounds and the compound 2-(2',4'-dichloro-5'-fluorobenzyl)-thiophene | BAYER AG (DE) | 1996-07-03 | — | — | EP | disclosed |