Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410103 | 0.83 | NPC1 (0.45) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL11314534 | 0.81 | L3MBTL1 (0.46) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL646103 | 0.79 | ABL1 (0.47) | NPC1RAB9AMAPK1LMNAABL1 | |
| SCHEMBL7410398 | 0.79 | ADCY10 (0.43) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL8916008 | 0.77 | TAAR1 (0.40) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL8917246 | 0.76 | TAAR1 (0.39) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL2097653 | 0.76 | IDO1 (0.65) | RAB9AMAPK1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7408044 | 0.76 | NPC1 (0.42) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL923302 | 0.73 | MEN1 (0.53) | NPC1RAB9AMAPK1LMNAL3MBTL1 | |
| SCHEMBL27959690 | 0.73 | NPC1 (0.56) | NPC1RAB9ALMNAABL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117019156-A | Supported metal cluster catalyst and preparation method thereof | 南京大学 | 2023-11-10 | — | — | CN | claimed |
| US-4661619-A | TREATMENT OF AROMATIC MERCAPTAN WITH CARBON MONOXIDE AND WATER OR ALCOHOL AND COBALT CARBONYL CATALYST | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1987-04-28 | — | — | US | claimed |
| CN-112714649-B | Cyclic dinucleotide derivatives and antibody drug conjugates thereof | 第一三共株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-106794174-B | Compounds for the treatment of cancer | GTX公司 | 2021-03-12 | — | — | CN | disclosed |
| US-7361743-B2 | Such as 5-propyl-azepane-2-carboxylic acid [2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydro-pyran-2-yl)-propyl]-amide; for prevention and treatment of mycobacterial, mycoplasmal or chlamydia infection; microbiocides | PFIZER INC (US) | 2008-04-22 | — | — | US | disclosed |
| US-7256177-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| EP-1814893-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| US-7199106-B2 | Lincomycin derivatives possessing antimicrobial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-20060148722-A1 | Novel lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-07-06 | — | — | US | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| EP-1644393-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIMICROBIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-0733044-A4 | COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5569677-A | TREATING PSORIASIS AND INFLAMMATORY BOWEL DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| EP-0732919-A1 | DIPHENYL-2-PROPENOATES AND HOMOLOGS THEREOF USEFUL FOR TREATING DISEASES ASSOCIATED WITH LEUKOTRIENE B4 | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0733044-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015752-A1 | DIPHENYL-2-PROPENOATES AND HOMOLOGS THEREOF USEFUL FOR TREATING DISEASES ASSOCIATED WITH LEUKOTRIENE B4 | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
| WO-1995015950-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |
| EP-0146291-B1 | PROCESS FOR THE PRODUCTION OF CARBOXYLIC ACIDS AND/OR ESTERS THEREOF | The British Petroleum Company p.l.c. (GB) | 1988-01-13 | — | — | EP | disclosed |
| US-4661619-A | TREATMENT OF AROMATIC MERCAPTAN WITH CARBON MONOXIDE AND WATER OR ALCOHOL AND COBALT CARBONYL CATALYST | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1987-04-28 | — | — | US | disclosed |
| EP-0146291-A1 | Process for the production of carboxylic acids and/or esters thereof | The British Petroleum Company p.l.c. (GB) | 1985-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148722-A1 | Novel lincomycin derivatives possessing antibacterial activity | LCLAT1, LAS1L, NRDC | NPC1 1694/4885RAB9A 799/4885MAPK1 3955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.